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Berberine+
  • Berberine+
  • Berberine+
  • Berberine+
  • Berberine+
Berberine+
NEW

Berberine+

1000mg

1000mg berberine with chromium, milk thistle, and absorption optimisers. Blood sugar and metabolism support.

  • Supports healthy blood sugar levels
  • Metabolism support
  • Liver support
  • Optimised for absorption and effectiveness
  • 1000mg berberine at clinical dose

What sets DRV+ apart

Berberine alone works. But berberine with wider support works better.

Most berberine supplements sell you berberine and nothing else. We add three things: 

Chromium, because it manages blood sugar and metabolism. Milk thistle, because Berberine may place demands on your liver which needs additional support. Alpha lipoic acid, because it has a role in the activated metabolic processes. BioPerine® black pepper extract, because it helps your body absorb all the nutrients.

KEY FEATURES

  • 1,000mg berberine HCl from Berberis aristata root bark at the clinical dose.
  • 200µg chromium picolinate for blood glucose and metabolism support.
  • 50mg milk thistle seed extract (standardised to 80% silymarins) to support your liver.
  • 200mg alpha lipoic acid which your body uses as a coenzyme.
  • 5mg BioPerine black pepper extract for optimal absorption.

WHAT TO EXPECT

Take it consistently for at least 12 weeks. Blood sugar and metabolism don't shift overnight. But with consistent use alongside a balanced diet, you'll enjoy steadier energy and sugar balance.

IMPORTANT

If you take any prescribed medication, are pregnant, breastfeeding or under medical supervision, speak to your doctor before use.

Nutrition information
PER 2 CAPSULESEC %NRV*
Berberine HCI1000mg**
Alpha Lipoic Acid200mg**
Milk Thistle Seed Extract 80% Silymarins Providing 1000mg Milk Thistle Seed50mg**
Chromium200ug500
Bioperine® Black Pepper5mg**
  • * NRV - Nutrient Reference Value
  • ** No NRV Established

Ingredients
INGREDIENTS: Berberine HCl (Berberis aristata), A-Lipoic Acid, Milk Thistle Seed Extract (Silybum Marianum), Bioperine® Black Pepper Extract (Piper nigrum), Chromium Picolinate, Capsule Shell (Hydroxypropyl Methylcellulose).

Free From: Added Sugar, Starch, Sweeteners, Gluten, Wheat, Soya, Lactose, Dairy, Artificial Flavours, Colours and Preservatives.

Directions

Take 2 capsules daily. Can be taken with or without food.

Drug interactions
Interaction severityDrug / drug classInteraction
MajorCyclosporineBerberine and black pepper may increase the blood level of this drug.
ModerateAnticoagulant / Antiplatelet DrugsBerberine, black pepper and alpha lipoic acid may increase the risk of bleeding when taken with these drugs.
ModerateAntidiabetes DrugsBerberine, chromium and milk thistle may increase the risk of hypoglycaemia when taken with these drugs.
ModerateAntihypertensive DrugsBerberine may increase the risk of hypotension when taken with these drugs.
ModerateCNS DepressantsBerberine may increase the risk of sedation when taken with these drugs.
ModerateCytochrome P450 2C9 (CYP2C9) SubstratesBerberine may increase the blood level of these drugs.
ModerateCytochrome P450 2D6 (CYP2D6) SubstratesBerberine and black pepper may increase the blood level of these drugs.
ModerateCytochrome P450 3A4 (CYP3A4) SubstratesBerberine and black pepper may increase the blood level of these drugs.
ModerateDextromethorphanBerberine may increase the blood level of this drug.
ModerateLosartanBerberine may decrease the effects of this drug.
ModerateMetforminBerberine may increase the effects of this drug.
ModerateMidazolamBerberine may increase the risk of side effects from this drug.
ModeratePentobarbitalBerberine and black pepper may increase the risk of sedation when taken with this drug.
ModerateTacrolimusBerberine may increase the blood level of this drug.
ModerateAlkylating AgentsAlpha lipoic acid may alter the effects of these drugs.
ModerateAntitumour AntibioticsAlpha lipoic acid may decrease the effectiveness of these drugs.
ModerateThyroid HormonesAlpha lipoic acid may decrease the effectiveness of these drugs.
ModerateGlucuronidated DrugsMilk thistle may affect the clearance of these drugs.
ModerateLedipasvirMilk thistle may affect the clearance of this drug.
ModerateMorphineMilk thistle may affect the level of this drug.
ModerateRaloxifeneMilk thistle may affect the clearance of this drug.
ModerateSirolimusMilk thistle may affect the clearance of this drug.
ModerateSofosbuvirMilk thistle may decrease the level of this drug.
ModerateTamoxifenMilk thistle may increase the level of this drug.
ModerateWarfarinMilk thistle may increase the level of this drug.
ModerateInsulinChromium may increase the risk of hypoglycaemia when taken with this drug.
ModerateLevothyroxineChromium might bind to levothyroxine in the intestinal tract and decrease levothyroxine absorption.
ModerateAtorvastatinBlack pepper may increase the level of this drug.
ModerateCytochrome P450 1A1 (CYP1A1) SubstratesBlack pepper may increase the level of drugs metabolised by CYP1A1.
ModerateCytochrome P450 2B1 (CYP2B1) SubstratesBlack pepper may increase the level of drugs metabolised by CYP2B1.
ModerateLithiumBlack pepper may increase the blood level of this drug.
ModerateNevirapineBlack pepper may increase the blood level of this drug.
ModerateP-glycoprotein SubstratesBlack pepper may increase the level of P-glycoprotein substrates.
ModeratePhenytoinBlack pepper may increase the blood level of this drug.
ModeratePropranololBlack pepper may increase the blood level of this drug.
ModerateRifampinBlack pepper may increase the blood level of this drug.
ModerateTheophyllineBlack pepper may increase the blood level of this drug.
  • Taken from Natural Medicines Database September 2026. Please do your own due diligence before recommending supplements alongside medicines.
FAQs
Clinically backed ingredients
Formulated by nutritionists
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5 ingredients - full dossier

Consistency is key

1 Week

Steady energy levels leading to reduced food cravings.

2 Weeks

Reduced food intake and a reduction in abdominal weight.

3 Weeks

 Improved liver support.

Still have questions?
We’ve got answers.

Can my client take Berberine+ with diabetes medication?

No, Berberine+ reduces blood sugar spikes, and when used with diabetes medication, it may cause hypoglycemia (low blood sugar).

Is Berberine+ a suitable alternative to medication?

Metabolic syndrome needs to be assessed by a healthcare provider. If the plan is to use diet and lifestyle as a first-line approach to reversing metabolic syndrome, Berberine+ is a fantastic addition to this. However, if your client's condition is past the point of using diet and lifestyle alone, Berberine+ is not a substitute for medication.

Claims for Berberine+

Chromium contributes to normal macronutrient metabolism.