OsteoFriend® donates to The Royal Osteoporosis Society

OsteoFriend^®

2bn live cultures

Advanced bone, muscle and joint formula. 19 active ingredients supporting the whole bone matrix with cofactors for nutrient absorption and collagen formation.

Bone density and strength
Muscles and connective tissues
High-strength calcium, D3, K2 and magnesium
Supports collagen formation
2 billion CFU live cultures
With curcumin, MSM, l-lysine

What sets DRV+ apart

Many bone supplements stop at calcium plus vitamin D. Your client's bones need more. The whole bone matrix is collagen (the structure) with minerals embedded in it. Provide only minerals, and it's building on a weak foundation.

OsteoFriend^® follows the whole bone matrix. High-absorption calcium, magnesium, vitamins D3 and K2. Vitamin C and L-lysine to fuel the body's own collagen formation. In powder form so your client gets evidence-based doses in one daily serving.

KEY FEATURES

740mg calcium, 320mg magnesium, 1,000IU vitamin D3, 100µg vitamin K2 clinically proven to support the maintenance of bones.
L-lysine (500mg) and Lactobacillus reuteri for absorption and nutrient delivery.
500mg vitamin C for collagen formation in bones and cartilage.
MSM for natural sulphur, with curcumin, boron and bamboo silica.
Zinc, manganese and copper for bones and connective tissue.
BioPerine black pepper for absorption.

THE BACKDROP

In our study of 343 women, 88% knew bone health is at risk after menopause and 77% were concerned about it.

Yet 42% rarely or never do weight-bearing exercise, the single most protective activity for bone health.
38% had taken a collagen supplement for their bones. The body breaks collagen down into amino acids, which is why OsteoFriend^® supplies vitamin C and L-lysine to fuel the body's own collagen formation.

WHAT TO EXPECT

Take for at least 2 months. The cycle by which old bone is replaced runs over months. Weight-bearing exercise alongside OsteoFriend^® does more than either alone.

Nutrition information

	PER 8.3g (1 tsp)	EC %NRV*
MSM	1000mg	**
Calcium	740mg	92
Magnesium	320mg	85
Curcumin	200mg	**
L-Lysine	500mg	**
Vitamin C	500mg	625
Vitamin D3	1000iu	500
Vitamin K2	100mcg	133
Vitamin B6	6mg	429
Folate	398mcg	199
Vitamin B12	200mcg	8000
Zinc	5mg	50
Boron	3mg	**
Copper	1mg	100
Manganese	1mg	50
Selenium	112mcg	204
Piperine (Black Pepper Extract)	5mg	**
Silica (Bamboo Extract)	5mg	**
Lactobacillus Reuteri	2 Billion CFU	***

* NRV - Nutrient Reference Value
** No NRV Established
*** At time of manufacture

Ingredients

INGREDIENTS: Calcium Citrate, Magnesium Citrate, MSM (Methylsulfonylmethane), L-Lysine Hydrochloride, Vitamin C (Ascorbic Acid), Curcumin (Turmeric Extract), Boron (Glycinate), Vitamin B12 (Methylcobalamin), Zinc (Citrate), Lactobacillus Reuteri (LR08), Vitamin D3 (Cholecalciferol), Manganese Citrate, Vitamin K2 (MK-7), Bamboo Extract, Vitamin B6 (Pyridoxal-5-Phosphate), Black Pepper (Piper Nigrum), Copper Citrate, Vitamin B9 (L-5 MTHF Calcium), Selenium (Selenomethionine).

FREE FROM: Added Sugar, Starch, Sweeteners, Gluten, Wheat, Soya, Lactose, Dairy, Artificial Flavours, Colours and Preservatives.

Directions

Take 1 teaspoon per day, morning or evening.

Mix or whisk into smoothies, yoghurts, cold drinks, or into cold food and stir well.

Do not exceed the recommended dose.

Drug interactions

Interaction severity	Drug / drug class	Interaction
Major	Dolutegravir	Calcium may reduce the effect of this drug.
Major	Elvitegravir	Calcium reduces the level of this drug.
Major	Levodopa	Magnesium may reduce the absorption of this drug.
Moderate	Atorvastatin	Vitamin D may reduce the absorption of this drug.
Moderate	Calcipotriene	Vitamin D may increase the risk of hypercalcaemia when taken with this drug.
Moderate	Thiazide Diuretics	Vitamin D may increase the risk of hypercalcaemia when taken with this drug.
Moderate	Verapamil	Calcium reduces the level of this drug.
Moderate	Bisphosphonates	Calcium and Magnesium may reduce the absorption of this drug. Take them at least 30 minutes apart.
Moderate	Calcipotriene	Calcium may increase the risk for hypercalcaemia when taken with this drug.
Moderate	Diltiazem	Calcium may reduce the effect of this drug.
Moderate	Levothyroxine	Calcium reduces the level of this drug. Take at least 4 hours apart.
Moderate	Lithium	Calcium may increase the risk for hypercalcemia when taken with this drug.
Moderate	Quinolone Antibiotics	Calcium, Magnesium, Zinc and Manganese reduce the level of this drug.
Moderate	Raltegravir	Calcium reduces the level of this drug.
Moderate	Sotalol	Apple Cider Vinegar, when taken with this drug, may increase the risk of hypokalaemia. Chromium may increase the risk of hypoglycemia when taken with this drug.
Moderate	Tetracycline Antibiotics	Calcium, Magnesium, Zinc and Manganese reduce the level of this drug.
Moderate	Thiazide Diuretics	Calcium may increase the risk of hypercalcaemia when taken with this drug.
Moderate	Aminoglycoside Antibiotics	Magnesium may increase the risk of neuromuscular weakness when taken with this drug.
Moderate	Calcium Channel Blockers	Magnesium may increase the effects of these drugs.
Moderate	Digoxin	Magnesium may reduce the absorption of this drug.
Moderate	Ketamine	Magnesium may increase the risk of ketamine toxicity.
Moderate	Potassium-Sparing Diuretics	Potassium-sparing diuretics decrease excretion of Magnesium.
Moderate	Sulfonylureas	Magnesium increases the absorption of these drugs.
Moderate	Anticoagulants / Antiplatelet Drugs	Selenium and Turmeric may increase the risk of bleeding when taken with these drugs.
Moderate	Barbiturates	Selenium may prolong the sedating effects of these drugs.
Moderate	Immunosuppressants	Selenium may reduce the effects of these drugs.
Moderate	Warfarin	Selenium, Vitamin C and Turmeric may reduce the effect of this drug. Reverse the effects of this drug.
Moderate	Cephalexin	Zinc may decrease the levels of this drug.
Moderate	Cisplatin	Zinc may reduce the effects of this drug.
Moderate	Integrase Inhibitors	Zinc may reduce the effects of this drug.
Moderate	Penicinillamine	Zinc and Copper may reduce the effects of this drug.
Moderate	Ritonavir	Zinc may reduce the effects of this drug.
Moderate	Antipsychotic Drugs	These drugs increase the risk of Manganese toxicity.
Moderate	Alkylating Agents	Vitamin C and Turmeric may reduce the effects of these drugs.
Moderate	Antitumor Antibiotics	Vitamin C and Turmeric may reduce the effects of these drugs.
Moderate	Oestrogens	Vitamin C may increase the blood level of these drugs.
Moderate	Fluphenazine	Vitamin C may reduce the effects of this drug.
Moderate	Indinavir	Vitamin C may reduce the effects of this drug.
Moderate	Levothyroxine	Vitamin C may increase the absorption of this drug.
Moderate	Amlodipine	Turmeric may increase the level of this drug.
Moderate	Antidiabetic Drugs	Turmeric may increase the risk of hypercalcaemia when taken with these drugs.
Moderate	Hepatotoxic Drugs	Turmeric may increase the risk of hepatotoxicity when taken with these drugs.
Moderate	Methotrexate	Turmeric and Folate may increase the effects of this drug.
Moderate	Organic Anion-transporting Polypeptide Substrates	Turmeric may increase the blood level of these drugs.
Moderate	Sulfasalazine	Turmeric may increase the side effects from this drug.
Moderate	Tacrolimus	Turmeric may increase the side effects from this drug.
Moderate	Talinolol	Turmeric may reduce the absorption of this drug.
Moderate	Tamoxifen	Turmeric may reduce the level of this drug.
Moderate	Topoisomerase 1 Inhibitors	Turmeric may reduce the activity of these drugs.
Moderate	Amiodarone	Vitamin B6 may increase the photosensitive effects from this drug.
Moderate	Antihypertensive Drugs	Vitamin B6 may increase the effects of these drugs.
Moderate	Phenobarbital	Vitamin B6 may decrease the effects of this drug. Folate may increase the risk of seizures from this drug.
Moderate	Phenytoin	Vitamin B6 and Folate may decrease the effects of this drug.
Moderate	Primidone	Folate may increase the risk of seizures from this drug.
Moderate	Pyrimethamine	Folate may decrease the effects of this drug.
Minor	Levodopa	Magnesium may reduce the absorption of this drug.

Drug interactions taken from the Natural Medicines Database, June 2025. Do your own diligence before combining food supplements and medicines.

FAQs

Clinically backed ingredients

Formulated by nutritionists

Connective tissue

Learn more

Endorsed by practitioners

This is a well-rounded, professional-grade supplement designed for bone, joint, and muscle support. A strong foundational supplement for someone looking to support musculoskeletal health, especially in conjunction with a nutrient-rich diet and weight-bearing exercise.

This is an excellent all-round supplement for bone and joint support. The formulation provides not just calcium and vitamin D, but also the key cofactors that help your body actually use these nutrients effectively. I would recommend this to my clients for long-term bone health.

I find the OsteoFriend formulation really exceptional in that it provides many nutrients that are essential for good bone health but often overlooked in many bone support formulations (such as vitamin K and boron) and I'm also really excited about the inclusion of L Reuters probiotic strains included here.

This is a thoughtful and comprehensive formula that goes beyond just calcium and vitamin D by addressing the multi-factorial nature of bone health in perimenopause. With high-quality forms of the key minerals and attention to dosing strategy, this is a great combination for skeletal health at midlife — especially when coupled with an antioxidant-rich, nutrient-dense diet and lifestyle modifications.

As a Nutritional Therapist specialising in women’s health, I really value the thoughtful formulation of OsteoFriend®. Unlike a standard calcium supplement, it brings together 19 active ingredients that work in synergy for bone, muscle, and joint health.

I am extremely impressed with OsteoFriend. 1 teaspoon a day provides all the necessary requirements for optimal bone health. Unlike many of the other bone support nutrients OsteoFriend contains no artificial sweeteners, flavours, preservatives or bulking agents. I highly recommend this excellent product.

Consistency is key

1 week

Nutrient intake increases and begins to address nutrient deficiencies.

2 weeks

Increased absorption of bone-supporting nutrients.

3 weeks

Osteoblasts start getting to work for stronger bones.

1 month+

Ongoing support for mobility, bone strength, and joint health.

Zero Additives

No Allergens

No Gluten

No Dairy or Lactose

No Soya

No Talc

No Palm Oil

No Bulking Agents

No Colourants

No Flavourants

No Parabens

No sugar, stevia or artificial sweeteners

Additives

100%

Naturally sourced & plant-based ingredients

100%

Active ingredients

How to enjoy

Measure

Measure 1 teaspoon
Drink

Stir well into water, smoothies or shakes
Eat

Or mix into yoghurts, smoothie bowls or cold / lukewarm meals

Still have questions?
We’ve got answers.

No, we recommend mixing it into cold drinks or sprinkling it onto cold or lukewarm food. This is because OsteoFriend® contains probiotics, which are sensitive to heat.

OsteoFriend® is the most comprehensive formula to help support strong, healthy bones. It contains 19 optimal ingredients, including calcium, magnesium vitamin D3, vitamin K2, curcumin, live cultures and more.

Yes, we recommend taking OsteoFriend® long-term. Looking after bones is a lifelong commitment.

We give 50p to The Royal Osteoporosis Society for every pack of OsteoFriend®, helping improve the lives of people affected by osteoporosis, and supporting research into bone health.

Lots of vitamins and minerals support healthier bones, the absorption of nutrients into bones, the delivery of nutrients into bone tissue, and the development of bone mass. Calcium, magnesium, MSM, omega 3, vitamins C, D3 and K2, and botanicals including turmeric can all support healthy bones and joints.

Calcium, Magnesium, Vitamin K2 and Vitamin D3 are essential for bones and muscles. OsteoFriend® contains these vitamins and minerals as well as many other proven nutrients to support bone health.

Both magnesium citrate and glycinate are great for bones. The citrate portion of magnesium citrate alkalises tissues, which leads to a higher level of calcium retention, while the glycine portion of magnesium glycinate enhances absorption of calcium.

OsteoFriend® provides unrivalled support for bones, muscles, and joints, with 19 active nutrients and cofactors supporting bone density, bone tissue and connective tissue. OsteoFriend® includes optimal doses of calcium, magnesium, vitamins D3 & K2, Curcumin, MSM, amino acids, and 2 billion live cultures (probiotics).

Yes. There are several nutrients that have been proven to support bone and joint health. Vitamin D enhances calcium absorption, and vitamin K2 takes the calcium into the bones. Vitamin C is needed for the collagen in both the bones and joints. Collagen is needed to help keep minerals in the bones and contributes to bone strength. In joints, collagen is needed as part of the lining of the joints. Some botanicals can also help reduce inflammation and support bone and joint health.

Claims for OsteoFriend®

Practitioner resources

Supplement considerations, practitioner papers and client handouts for this product, to read online or download as PDF.

Supplement considerations

Osteoporosis Supplements and Tests: DEXA, Vitamin D & Bone Markers
Supplement, diet, lifestyle and testing considerations.
Download PDF
Supplement considerations

Osteoarthritis Supplements and Tests: A Practitioner Guide
Supplement, diet, lifestyle and testing considerations
Download PDF

View all

OsteoFriend®

What sets DRV+ apart

Nutrition information

Ingredients

Directions

Drug interactions

19 ingredients - full dossier

Endorsed by practitioners

Consistency is key

Naturally effective supplements

How to enjoy

Measure

Drink

Eat

Still have questions? We’ve got answers.

Can my client mix OsteoFriend® into hot foods / drinks?

What makes OsteoFriend® different rom other bone and muscle support supplements?

Can my client take OsteoFriend® long-term?

How does OsteoFriend® support The Royal Osteoporosis Society?

What are the best supplements to take for osteoarthritis?

Which vitamin is good for bones and muscles?

Which magnesium is best for bones and muscles?

What supplements are good for bone health?

Can supplements improve bone and joint health?

Claims for OsteoFriend®

Practitioner resources

OsteoFriend^®

Still have questions?
We’ve got answers.